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中文名称：NCOA4 抗原（重组蛋白）
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Full name: |
nuclear receptor coactivator 4 |
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Synonyms: |
RFG; ELE1; PTC3; ARA70 |
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Swissprot: |
Q13772 |
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Gene Accession: |
BC012736 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes an androgen receptor coactivator. The encoded protein interacts with the androgen receptor in a ligand-dependent manner to enhance its transcriptional activity. Chromosomal translocations between this gene and the ret tyrosine kinase gene, also located on chromosome 10, have been associated with papillary thyroid carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes are present on chromosomes 4, 5, 10, and 14. |
