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Ó¢ÎÄÃû³Æ£º Anti-ANAPC5 rabbit polyclonal antibody
±ð Ãû£º APC5
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¿¹ Ô£º ANAPC5
´¢ ´æ£º Àä¶³£¨-20¡æ£©
ËÞ Ö÷£º Rabbit
·´Ó¦ÖÖÊô£º Human, Mouse, Rat
±ê ¼Ç Î Unconjugate
¿Ë¡ÀàÐÍ£º rabbit polyclonal
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Background: |
This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
ANAPC5 |
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Immunogen: |
Fusion protein of human ANAPC5 |
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Full name: |
anaphase promoting complex subunit 5 |
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Synonyms£º |
APC5 |
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SwissProt: |
Q9UJX4 |
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ELISA Recommended dilution: |
1000-5000 |
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IHC positive control: |
Human thyroid cancer and human liver cancer |
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IHC Recommend dilution: |
50-200 |
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021-54845833/15800441009
