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ÖÐÎÄÃû³Æ£º Íÿ¹ANAPC5¶à¿Ë¡¿¹Ìå

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Anti-ANAPC5 rabbit polyclonal antibody

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APC5

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¿¹      Ô­£º ANAPC5

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ËÞ      Ö÷£º Rabbit

·´Ó¦ÖÖÊô£º Human, Mouse, Rat

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rabbit polyclonal

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Background:

This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, IHC

Name of antibody:

ANAPC5

Immunogen:

Fusion protein of human ANAPC5

Full name:

anaphase promoting complex subunit 5

Synonyms£º

APC5

SwissProt:

Q9UJX4

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human thyroid cancer and human liver cancer

IHC Recommend dilution:

50-200




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