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中文名称：TLE6 抗原（重组蛋白）
英文名称： TLE6 Antigen (Recombinant Protein)
别 名： transducin like enhancer of split 6; GRG6; PREMBL
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 373-572 amino acids of human TLE6 |
|
Full name: |
transducin like enhancer of split 6 |
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Synonyms: |
GRG6; PREMBL |
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Swissprot: |
Q9H808 |
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Gene Accession: |
BC020206 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a member of the Groucho/ transducin-like Enhancer of split family of transcriptional co-repressors. The encoded protein is a component of the mammalian subcortical maternal complex, which is required for preimplantation development. In mouse, knock out of this gene results in cleavage-stage embryonic arrest resulting from defective cytoplasmic F-actin meshwork formation and asymmetric cell division. In human, an allelic variant in this gene is associated with preimplantation embryonic lethality. Alternative splicing results in multiple transcript variants. |
