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Ó¢ÎÄÃû³Æ£ºEGR1 Antigen (Recombinant Protein)

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Fusion protein corresponding to a region derived from 87-337 amino acids of human EGR1


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Full name:

early growth response 1

Synonyms:

TIS8, AT225, G0S30, NGFI-A, ZNF225, KROX-24, ZIF-268

Swissprot:

P18146

Gene Accession:

BC073983

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

EGR-1 (Early growth response protein 1) also known as Zif268 (zinc finger protein 225) or NGFI-A (nerve growth factor-induced protein A) is a protein that in humans is encoded by the EGR1 gene. The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site).


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