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Ó¢ÎÄÃû³Æ£º XRCC4 Antigen (Recombinant Protein)

±ð     Ãû£º X-ray repair cross complementing 4; SSMED

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Fusion protein corresponding to a region derived from 1-336 amino acids of human XRCC4

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Full name:

X-ray repair cross complementing 4

Synonyms:

SSMED

Swissprot:

Q13426

Gene Accession:

BC016314

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V(D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternative splicing generates several transcript variants.


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