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中文名称：YARS2抗原（重组蛋白）
英文名称： YARS2 Antigen (Recombinant Protein)
别 名： TYRRS; CGI-04; MLASA2; MT-TYRRS
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to C terminal 300 amino acids of human YARS2 |
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Full name: |
tyrosyl-tRNA synthetase 2, mitochondrial |
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Synonyms: |
TYRRS; CGI-04; MLASA2; MT-TYRRS |
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Swissprot: |
Q9Y2Z4 |
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Gene Accession: |
BC015625 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a mitochondrial protein that catalyzes the attachment of tyrosine to tRNA(Tyr). Mutations in this gene are associated with myopathy with lactic acidosis and sideroblastic anemia type 2 (MLASA2). Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr). |
