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中文名称：LTA 抗原（重组蛋白）
英文名称： LTA Antigen (Recombinant Protein)
别 名： lymphotoxin alpha (TNF superfamily, member 1); LT; TNFB; TNFSF1
储 存： 冷冻（-20℃）
概 述：
|
Fusion protein corresponding to a region derived from 36-205 amino acids of human LTA |
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Full name: |
lymphotoxin alpha (TNF superfamily, member 1) |
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Synonyms: |
LT; TNFB; TNFSF1 |
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Swissprot: |
P01374 |
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Gene Accession: |
BC034729 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4, myocardial infarction, non-Hodgkin's lymphoma, and psoriatic arthritis. Alternatively spliced transcript variants have been observed for this gene. |
