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中文名称： LIN37 抗原（重组蛋白）
英文名称： LIN37 Antigen (Recombinant Protein)
别 名： lin-37 DREAM MuvB core complex component; F25965; lin-37; ZK418.4
相关类别： 抗原
储 存： 冷冻（-20℃）
概 述
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Fusion protein corresponding to a region derived from 1-246 amino acids of human LIN37 |
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Full name: |
lin-37 DREAM MuvB core complex component |
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Synonyms: |
F25965; lin-37; ZK418.4 |
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Swissprot: |
Q96GY3 |
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Gene Accession: |
BC009071 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The LIN proteins regulate an intercellular signaling process that induces formation of the hermaphrodite vulva in C. elegans by acting to prevent the activation of a receptor tyrosine kinase/Ras signaling pathway. LIN37 is a 246 amino acid protein that is a mammalian homolog of the C. elegans Lin-37 protein. LIN37 functions as a component of the DREAM complex (also known as the LINC complex), which is comprised of several proteins, all of which work in concert to repress cell cycle-dependent genes. LIN37 is encoded by a gene located on human chromosome 19q13.2. |
