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中文名称：SPIRE2抗原（重组蛋白）
英文名称： SPIRE2 Antigen (Recombinant Protein)
别 名： Spir-2
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to C terminal 250 amino acids of human SPIRE2 |
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Full name: |
spire-type actin nucleation factor 2 |
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Synonyms: |
Spir-2 |
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Swissprot: |
Q8WWL2 |
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Gene Accession: |
BC139732 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
SPIRE2, is a 714 amino acid protein belonging to the spire family. Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning and asymmetric cell division during meiosis. Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis. |
