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中文名称：PFKP抗原（重组蛋白）
英文名称： PFKP Antigen (Recombinant Protein)
别 名： PFKF; PFK-C
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
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Fusion protein corresponding to C terminal 250 amino acids of human PFKP |
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Full name: |
phosphofructokinase, platelet |
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Synonyms: |
PFKF; PFK-C |
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Swissprot: |
Q01813 |
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Gene Accession: |
BC002536 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11). PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM; MIM 610681) and liver (PFKL; MIM 171860) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora (1981) [PubMed 6451249] determined that full tetrameric phophofructokinase enzyme expressed in platelets can be composed of subunits P4, P3L, and P2L2 |
