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ÖÐÎÄÃû³Æ£º MVP¿¹Ô­£¨ÖØ×éµ°°×£©

Ó¢ÎÄÃû³Æ£º MVP Antigen (Recombinant Protein)

±ð      Ãû£º LRP, VAULT1

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Fusion protein corresponding to a C terminal 300 amino acids of human MVP

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Full name:

major vault protein

Synonyms:

LRP, VAULT1

Swissprot:

Q14764

Gene Accession:

BC015623

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene.

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