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Ó¢ÎÄÃû³Æ£º FUS Antigen (Recombinant Protein)

±ð      Ãû£ºFUS RNA binding protein; TLS; ALS6; ETM4; FUS1; POMP75; HNRNPP2

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Fusion protein corresponding to C terminal 77 amino acids of human FUS


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Full name:

FUS RNA binding protein

Synonyms:

TLS; ALS6; ETM4; FUS1; POMP75; HNRNPP2

Swissprot:

P35637

Gene Accession:

BC000402

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.


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