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中文名称： CARD8抗原（重组蛋白）
英文名称： CARD8 Antigen (Recombinant Protein)
别 名： NDPP; DACAR; DAKAR; NDPP1; TUCAN; CARDINAL
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to C terminal 250 amino acids of human CARD8 |
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Full name: |
caspase recruitment domain family, member 8 |
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Synonyms: |
NDPP; DACAR; DAKAR; NDPP1; TUCAN; CARDINAL |
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Swissprot: |
Q9Y2G2 |
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Gene Accession: |
BC056891 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. |
