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中文名称： CABLES1抗原（重组蛋白）
英文名称： CABLES1 Antigen (Recombinant Protein)
别 名： CABL1; IK3-1; CABLES; HsT2563
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to C terminal 250 amino acids of human CABLES1 |
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Full name: |
Cdk5 and Abl enzyme substrate 1 |
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Synonyms: |
CABL1; IK3-1; CABLES; HsT2563 |
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Swissprot: |
Q8TDN4 |
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Gene Accession: |
BC037218 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene. |
