ÖÐÎÄÃû³Æ£º Íÿ¹ALAS1¶à¿Ë¡¿¹Ìå
Ó¢ÎÄÃû³Æ£º Anti-ALAS1 rabbit polyclonal antibody
±ð Ãû£º ALAS; MIG4; ALAS3; ALASH
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¿¹ Ô£º ALAS1
ËÞ Ö÷£º Rabbit
·´Ó¦ÖÖÊô£º Human, Mouse, Rat
±ê ¼Ç Î Unconjugate
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Background: |
This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
ALAS1 |
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Immunogen: |
Fusion protein of human ALAS1 |
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Full name: |
aminolevulinate, delta-, synthase 1 |
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Synonyms£º |
ALAS; MIG4; ALAS3; ALASH |
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SwissProt: |
P13196 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human breast cancer and human thyroid cancer |
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IHC Recommend dilution: |
25-100 |
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021-54845833/15800441009
