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ÖÐÎÄÃû³Æ£º DCD ¿¹Ô­£¨ÖØ×éµ°°×£©

Ó¢ÎÄÃû³Æ£º DCD Antigen (Recombinant Protein)

±ð     Ãû£º dermcidin; PIF; AIDD; DSEP; HCAP; DCD-1

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Fusion protein corresponding to a region derived from 20-109 amino acids of human DCD

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Full name:

dermcidin

Synonyms:

PIF; AIDD; DSEP; HCAP; DCD-1

Swissprot:

P81605

Gene Accession:

BC062682

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This antimicrobial gene encodes a secreted protein that is subsequently processed into mature peptides of distinct biological activities. The C-terminal peptide is constitutively expressed in sweat and has antibacterial and antifungal activities. The N-terminal peptide, also known as diffusible survival evasion peptide, promotes neural cell survival under conditions of severe oxidative stress. A glycosylated form of the N-terminal peptide may be associated with cachexia (muscle wasting) in cancer patients. Alternative splicing results in multiple transcript variants encoding different isoforms.



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