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中文名称：PPP1R1A抗原（重组蛋白）
英文名称： PPP1R1A Antigen (Recombinant Protein)
别 名： I1; IPP1
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 1-171 amino acids of human PPP1R1A |
|
Full name: |
protein phosphatase 1 regulatory inhibitor subunit 1A |
|
Synonyms: |
I1; IPP1 |
|
Swissprot: |
Q13522 |
|
Gene Accession: |
BC022470 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases. |
