购物车
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021-54845833/15800441009
中文名称： BTK抗原（重组蛋白）
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Full name: |
Bruton tyrosine kinase |
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Synonyms: |
AT; ATK; BPK; XLA; IMD1; AGMX1; PSCTK1 |
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Swissprot: |
Q06187 |
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Gene Accession: |
BC109079 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms. |
