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ÖÐÎÄÃû³Æ£ºÍÿ¹AKR1C4¶à¿Ë¡¿¹Ìå 

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Anti-AKR1C4 rabbit polyclonal antibody

±ð      Ãû£º C11; CDR; DD4; CHDR; DD-4; HAKRA; 3-alpha-HSD

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¿¹      Ô­£º AKR1C4

ËÞ      Ö÷£º Rabbit

·´Ó¦ÖÖÊô£º Human, Mouse

±ê ¼Ç Î Unconjugate

¿Ë¡ÀàÐÍ£º rabbit polyclonal

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Background:

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.

Applications:

ELISA, WB, IHC

Name of antibody:

AKR1C4

Immunogen:

Full length fusion protein

Full name:

aldo-keto reductase family 1, member C4

Synonyms£º

C11; CDR; DD4; CHDR; DD-4; HAKRA; 3-alpha-HSD

SwissProt:

P17516

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

37 kDa

WB Positive control:

HEPG2 cell lysate

WB Recommended dilution:

500-2000




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