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中文名称：ACTR1A 抗原（重组蛋白）
英文名称： ACTR1A Antigen (Recombinant Protein)
别 名： actin related protein 1A; ARP1; Arp1A; CTRN1
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 127-376 amino acids of human ACTR1A |
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Full name: |
actin related protein 1A |
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Synonyms: |
ARP1; Arp1A; CTRN1 |
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Swissprot: |
P61163 |
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Gene Accession: |
BC000693 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin. |
