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中文名称：APLNR抗原（重组蛋白）
英文名称：APLNR Antigen (Recombinant Protein)
储 存：冷冻（-20℃）
相关类别：抗原
概述
|
Fusion protein corresponding to a region derived from 272-380 amino acids of human APLNR |
技术规格
|
Full name: |
apelin receptor |
|
Synonyms: |
APJ, APJR, HG11, AGTRL1 |
|
Swissprot: |
P35414 |
|
Gene Accession: |
BC032688 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified. |
