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Íÿ¹CPS1¶à¿Ë¡¿¹Ìå


Ó¢ÎÄÃû³Æ£º Anti-CPS1 rabbit polyclonal antibody

±ð      Ãû£º carbamoyl-phosphate synthase 1 PHN; CPSASE1

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ËÞ      Ö÷£º Rabbit

¿¹      Ô­£º CPS1

·´Ó¦ÖÖÊô£º Human, Mouse, Rat

±ê  ¼Ç Î Unconjugate

¿Ë¡ÀàÐÍ£º rabbit polyclonal

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Background:

The mitochondrial enzyme encoded by this gene catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells. The encoded protein may also represent a core mitochondrial nucleoid protein. Three transcript variants encoding different isoforms have been found for this gene. The shortest isoform may not be localized to the mitochondrion. Mutations in this gene have been associated with carbamoyl phosphate synthetase deficiency, susceptibility to persistent pulmonary hypertension, and susceptibility to venoocclusive disease after bone marrow transplantation.

Applications:

ELISA, IHC

Name of antibody:

CPS1

Immunogen:

Synthetic peptide of human CPS1

Full name:

carbamoyl-phosphate synthase 1

Synonyms:

PHN; CPSASE1

SwissProt:

P31327

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer and Human lung cancer

IHC Recommend dilution:

30-150




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