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中文名称：兔抗ANLN多克隆抗体
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Background: |
Anillin, also known as scraps homolog, is an evolutionarily conserved Actin- binding protein required for cytokinesis that was first identified in Drosophila melanogaster. Anillin is a ubiquitously expressed protein with highest expression levels in the central nervous system. It is predominantly found in the nucleus and it localizes to the cleavage furrow during cytokinesis, forming a ring with the help of Rac GTPase. During cytokinesis, Anillin interacts with CD2AP and functions to concentrate Rho A and maintain the localization of active Myosin. In Anillin knockout cells the cleavage furrow fails to complete ingression. Anillin expression levels fluctuate with the cell cycle, peaking in mitosis. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
ANLN |
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Immunogen: |
Fusion protein of human ANLN |
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Full name: |
anillin, actin binding protein |
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Synonyms： |
scra; Scraps |
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SwissProt: |
Q9NQW6 |
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ELISA Recommended dilution: |
1000-2000 |
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IHC positive control: |
Human brain |
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IHC Recommend dilution: |
25-100 |
