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中文名称：兔抗CNOT2(Ab-101) 多克隆抗体
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Background: |
Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Required for the CCR4-NOT complex structural integrity. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation; the repressive function may specificly involve the N-Cor repressor complex containing HDAC3, NCOR1 and NCOR2. Involved in the maintenance of emryonic stem (ES) cell identity. |
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Applications: |
WB |
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Name of antibody: |
CNOT2(Ab-101) |
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Immunogen: |
Synthesized non-phosphopeptide derived from human CNOT2 around the phosphorylation site of serine 101 (S-L-S(p)-Q-G). |
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Full name: |
CCR4-NOT transcription complex, subunit 2 |
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Synonyms： |
NOT2; CDC36; NOT2H; HSPC131 |
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SwissProt: |
Q9NZN8 |
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WB Predicted band size: |
60 kDa |
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WB Positive control: |
HepG2 cells treated with starved (24hours) lysate |
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WB Recommended dilution: |
500-3000 |
