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021-54845833/15800441009
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Background: |
The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
VAMP2 |
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Immunogen: |
Synthetic peptide of humanVAMP2 |
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Full name: |
vesicle-associated membrane protein 2 (synaptobrevin 2) |
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Synonyms： |
SYB2; VAMP-2 |
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SwissProt: |
P63027 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human thyroid cancer and Human esophagus cancer |
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IHC Recommend dilution: |
25-100 |
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WB Predicted band size: |
13 kDa |
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WB Positive control: |
A172, Jurkat and Hela cells, Mouse brain and Human fetal brain tissue |
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WB Recommended dilution: |
500-2000 |
