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ÖÐÎÄÃû³Æ£º Íÿ¹PLAAT3¶à¿Ë¡¿¹Ìå


Ó¢ÎÄÃû³Æ£º Anti-PLAAT3 rabbit polyclonal antibody


±ð       Ãû£º phospholipase A and acyltransferase 3; AdPLA; HRSL


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´¢       ´æ£º Àä¶³£¨-20¡æ£©


ËÞ       Ö÷£º Rabbit


¿¹       Ô­£º PLAAT3


·´Ó¦ÖÖÊô£º Human, Mouse, Rat


±ê  ¼Ç  Î Unconjugate


¿Ë¡ÀàÐÍ£º rabbit polyclonal


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IHC Recommend dilution:

30-150

IHC positive control:

Human thyroid cancer and Human tonsil

SwissProt:

P53816

Synonyms:

AdPLA; HRSL3; HRASLS3; HREV107; PLA2G16; PLAAT-3; H-REV107; HREV107-1; HREV107-3; H-REV107-1

Full name:

phospholipase A and acyltransferase 3

Immunogen:

Synthetic peptide of human PLAAT3

Name of antibody:

PLAAT3

Applications:

ELISA, IHC

Background:

Exhibits both phospholipase A1/2 and acyltransferase activities (PubMed:19615464, PubMed:19047760, PubMed:22825852, PubMed:22605381, PubMed:26503625). Shows phospholipase A1 (PLA1) and A2 (PLA2) activity, catalyzing the calcium-independent release of fatty acids from the sn-1 or sn-2 position of glycerophospholipids (PubMed:19615464, PubMed:19047760, PubMed:22825852, PubMed:22605381, PubMed:22923616). For most substrates, PLA1 activity is much higher than PLA2 activity (PubMed:19615464). Shows O-acyltransferase activity,catalyzing the transfer of a fatty acyl group from glycerophospholipid to the hydroxyl group of lysophospholipid (PubMed:19615464). Shows N-acyltransferase activity, catalyzing the calcium-independent transfer of a fatty acyl group at the sn-1 position of phosphatidylcholine (PC) and other glycerophospholipids to the primary amine of phosphatidylethanolamine (PE), forming N-acylphosphatidylethanolamine (NAPE), which serves as precursor for N-acylethanolamines (NAEs) (PubMed:19615464, PubMed:19047760, PubMed:22825852, PubMed:22605381). Exhibits high N-acyltransferase activity and low phospholipase A1/2 activity (PubMed:22825852).






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