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021-54845833/15800441009
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Background: |
DsbA has a role in cytochrome C synthesis. Required for disulfide bond formation in some periplasmic proteins such as PhoA or OmpA. Acts by transferring its disulfide bond to other proteins and is reduced in the process. DsbA is reoxidized by DsbB. Required for pilus biogenesis. PhoP-regulated transcription is redox-sensitive, being activated when the periplasm becomes more reducing (deletion of dsbA/dsbB, treatment with dithiothreitol). MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway. |
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Applications: |
WB |
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Name of antibody: |
DsbA-Tag |
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Immunogen: |
Fusion protein of E.coli DsbA-Tag |
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Full name: |
periplasmic protein disulfide isomerase I |
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Synonyms: |
dsf; ECK3852; iarA; JW3832; ppfA |
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SwissProt: |
P0AEG4 |
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WB Predicted band size: |
23 kDa |
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WB Positive control: |
DsbA with DsbA recombinant protein |
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WB Recommended dilution: |
1000-5000 |
