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Ó¢ÎÄÃû³Æ£º Anti-ACOD1 rabbit polyclonal antibody
±ð Ãû£º aconitate decarboxylase 1; CAD; IRG1
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ËÞ Ö÷£º Rabbit
¿¹ Ô£º ACOD1
·´Ó¦ÖÖÊô£º Human, Mouse
±ê ¼Ç Î Unconjugate
¿Ë¡ÀàÐÍ£º rabbit polyclonal
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Background: |
Involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells; ACOD1-mediated itaconic acid production contributes to the antimicrobial activity of macrophages. Plays a role in the embryo implantation. |
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Applications: |
ELISA, WB |
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Name of antibody: |
ACOD1 |
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Immunogen: |
Synthetic peptide of human ACOD1 |
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Full name: |
aconitate decarboxylase 1 |
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Synonyms: |
CAD; IRG1 |
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SwissProt: |
A6NK06 |
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ELISA Recommended dilution: |
5000-10000 |
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WB Predicted band size: |
53 kDa |
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WB Positive control: |
Mouse heart tissue and K562 cell lysates |
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WB Recommended dilution: |
500-2000 |

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021-54845833/15800441009
