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Fusion protein corresponding to a region derived from 32-266 amino acids of human DKK1 |
技术规格
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Full name: |
dickkopf WNT signaling pathway inhibitor 1 |
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Synonyms: |
SK; DKK-1 |
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Swissprot: |
O94907 |
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Gene Accession: |
BC001539 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. |
