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中文名称：IRF4抗原（重组蛋白）
英文名称： IRF4 Antigen (Recombinant Protein)
别 名： MUM1; LSIRF; SHEP8; NF-EM5
储 存： 冷冻（-20℃）
相关类别： 抗原
概述
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Fusion protein corresponding to a region derived from 129-451 amino acids of human IRF4 |
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Full name: |
interferon regulatory factor 4 |
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Synonyms: |
MUM1; LSIRF; SHEP8; NF-EM5 |
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Swissprot: |
Q15306 |
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Gene Accession: |
BC015752 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. |
