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    ÖÐÎÄÃû³Æ£ºDCN¿¹Ô­£¨ÖØ×éµ°°×£©

    Ó¢ÎÄÃû³Æ£ºDCN Antigen (Recombinant Protein)

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    Fusion protein corresponding to a region derived from 60-359 amino acids of human DCN


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    Full name:

    decorin

    Synonyms:

    CSCD; PG40; PGII; PGS2; DSPG2; SLRR1B

    Swissprot:

    P07585

    Gene Accession:

    BC005322

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    This gene encodes a member of the small leucine-rich proteoglycan family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. This protein plays a role in collagen fibril assembly. Binding of this protein to multiple cell surface receptors mediates its role in tumor suppression, including a stimulatory effect on autophagy and inflammation and an inhibitory effect on angiogenesis and tumorigenesis. This gene and the related gene biglycan are thought to be the result of a gene duplication. Mutations in this gene are associated with congenital stromal corneal dystrophy in human patients.



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