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中文名称： LIG1抗原（重组蛋白）
英文名称： LIG1 Antigen (Recombinant Protein)
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to a region derived from C terminal 250 amino acids of human LIG1 |
|
Full name: |
ligase I, DNA, ATP-dependent |
|
Swissprot: |
P18858 |
|
Gene Accession: |
BC110622 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants. |
