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CNNM3 Antigen (Recombinant Protein)

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Fusion protein corresponding to C terminal 300 amino acids of human CNNM3


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Full name:

cyclin and CBS domain divalent metal cation transport mediator 3

Synonyms:

ACDP3

Swissprot:

Q8NE01

Gene Accession:

BC007199

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The ACDP3 gene, designated CNNM3 by the HUGO Nomenclature Committee, encodes a deduced 707-amino acid protein. Northern blot analysis revealed ubiquitous expression of CNNM3. Immunofluorescence studies showed that all 4 CNMM proteins are predominantly localized in the nucleus. Acdp3 contains 4 transmembrane domains, 2 CBS domains, a DUF21 domain, and a cNMP-binding domain. It also has large alanine- and leucine-rich regions. Northern blot analysis detected variable Acdp3 expression in all mouse tissues examined, with highest expression in brain, kidney, liver, and heart.


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