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技术规格
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Background: |
May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit |
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Applications: |
IHC |
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Name of antibody: |
IRS1(Phospho-Ser307) |
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Immunogen: |
Peptide sequence around phosphorylation site of serine 307(T-E-S(p)-I-T) derived from Human IRS-1. |
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Full name: |
insulin receptor substrate 1 |
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Synonyms： |
HIRS-1 |
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SwissProt: |
P35568 |
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IHC positive control: |
Human breast carcinoma tissue |
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IHC Recommend dilution: |
50-100 |
