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Background: |
Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
FGL1 |
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Immunogen: |
Fusion protein of human FGL1 |
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Full name: |
fibrinogen-like 1 |
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Synonyms： |
HFREP1; HP-041; LFIRE1; LFIRE-1 |
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SwissProt: |
Q08830 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human liver cancer |
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IHC Recommend dilution: |
50-200 |
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WB Predicted band size: |
36 kDa |
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WB Positive control: |
Human fetal liver tissue |
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WB Recommended dilution: |
500-2000 |
