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Background: |
This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
IRAK3 |
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Immunogen: |
Fusion protein of human IRAK3 |
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Full name: |
interleukin-1 receptor-associated kinase 3 |
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Synonyms： |
ASRT5; IRAKM |
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SwissProt: |
Q9Y616 |
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ELISA Recommended dilution: |
1000-2000 |
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IHC positive control: |
Human thyroid cancer |
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IHC Recommend dilution: |
25-100 |
