购物车
帮助
021-54845833/15800441009
|
Background: |
This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. |
|
Applications: |
ELISA, IHC |
|
Name of antibody: |
IKZF3 |
|
Immunogen: |
Fusion protein of human IKZF3 |
|
Full name: |
IKAROS family zinc finger 3 (Aiolos) |
|
Synonyms： |
AIO; AIOLOS; ZNFN1A3 |
|
SwissProt: |
Q9UKT9 |
|
ELISA Recommended dilution: |
1000-5000 |
|
IHC positive control: |
Human liver cancer and human thyroid cancer |
|
IHC Recommend dilution: |
50-200 |
