购物车
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021-54845833/15800441009
Background:
FXN, also named as FRDA, X25, m81-FXN, d-FXN, m78-FXN and i-FXN, belongs to the frataxin family. It promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. FXN may play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+; the oligomeric form but not the monomeric form has in vitro ferroxidase activity. FXN is cleaved to be 4 chains. The mature form of FXN is 14kd or 18kd.
Applications:
WB
Name of antibody:
FXN
Immunogen:
Fusion protein of human FXN
Full name:
frataxin
Synonyms：
CyaY; FA; FARR; FRDA; MGC57199; X25
SwissProt:
Q16595
WB Predicted band size:
23 kDa
WB Positive control:
MDA-MB-453s cells
WB Recommended dilution:
500-2000
