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021-54845833/15800441009
中文名称： 兔抗HIRA多克隆抗体
英文名称： Anti-HIRA rabbit polyclonal antibody
别 名： TUP1; DGCR1; TUPLE1
储 存： 冷冻（-20℃）
宿 主： Rabbit
抗 原： HIRA
标 记 物： Unconjugate
克隆类型： rabbit polyclonal
技术规格
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Background: |
This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
HIRA |
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Immunogen: |
Synthetic peptide of human HIRA |
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Full name: |
histone cell cycle regulator |
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Synonyms： |
TUP1; DGCR1; TUPLE1 |
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SwissProt: |
P54198 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human brain |
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IHC Recommend dilution: |
20-100 |
