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  • Íÿ¹PPP1R8¶à¿Ë¡¿¹Ìå

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    • Ŀ¼ºÅ : TW21887
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ÖÐÎÄÃû³Æ :   Íÿ¹PPP1R8¶à¿Ë¡¿¹Ìå


Ó¢ÎÄÃû³Æ :    Anti-PPP1R8 rabbit polyclonal antibody


±ð      Ãû :   ARD1; ARD-1; NIPP1; NIPP-1; PRO2047


¿¹      Ô­ :    PPP1R8


´¢      ´æ :   Àä¶³£¨-20¡æ£© ±Ü¹â


ËÞ      Ö÷ :   Rabbit


·´Ó¦ÖÖÊô :   Human Mouse


Ïà¹ØÀà±ð :   Ò»¿¹


±ê  ¼Ç  Îï :   Unconjugate


¿Ë¡ÀàÐÍ :   rabbit polyclonal


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Background:

This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.

Applications:

WB

Name of antibody:

PPP1R8

Immunogen:

Synthesized peptide derived from internal of human PPP1R8.

Full name:

protein phosphatase 1, regulatory subunit 8

Synonyms£º

ARD1; ARD-1; NIPP1; NIPP-1; PRO2047

SwissProt:

Q12972

WB Predicted band size:

38 kDa

WB Positive control:

Jurkat cells lysate

WB Recommended dilution:

500-3000




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