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      Ó¢ÎÄÃû³Æ£º Anti-MTHFD2 mouse monoclonal antibody

      ±ð       Ãû£º methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase; NMDMC

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      ËÞ       Ö÷£º Mouse

      ¿¹       Ô­£º MTHFD2

      ·´Ó¦ÖÖÊô£º Human

      ±ê  ¼Ç  Î Unconjugate

      ¿Ë¡ÀàÐÍ£º mouse monoclonal

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      Background:

      This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7.

      Applications:

      ELISA, WB

      Name of antibody:

      MTHFD2

      Immunogen:

      Fusion protein of human MTHFD2

      Full name:

      methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase

      Synonyms:

      NMDMC

      SwissProt:

      P13995

      WB Predicted band size:

      38 kDa

      WB Positive control:

      HeLa whole cell lysate

      WB Recommended dilution:

      500-2000




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