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ÖÐÎÄÃû³Æ£º Íÿ¹AD7C-NTP¶à¿Ë¡¿¹Ìå


Ó¢ÎÄÃû³Æ£º Anti-AD7C-NTP rabbit polyclonal antibody

±ð      Ãû£º AD7CNTP

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´¢      ´æ£º Àä¶³£¨-20¡æ£©

ËÞ      Ö÷£º Rabbit

¿¹      Ô­£º AD7C-NTP

·´Ó¦ÖÖÊô£º Human

±ê ¼Ç Î Unconjugate

¿Ë¡ÀàÐÍ£º rabbit polyclonal

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Background:

The predicted AD7CNTP protein contains 375 amino acids and has a calculate molecular mass of about 42 kD. It is rich in serine and proline residues, has a 15-amino acid hydrophobic leader sequence, and has 7 putative membrane-spanning regions. AD7CNTP has several phosphorylation sites, a myristoylation site, and 2 serine/threonine kinase protein domains. Northern blot analysis detected 1.4- and 0.9-kb transcripts only in adult frontal and temporal lobe. In vitro studies demonstrated that overexpression of AD7CNTP in transfected neuronal cells promoted neuritic sprouting and cell death, the 2 principal neuroanatomic lesions correlated with dementia in AD.

Applications:

ELISA, WB, IHC

Name of antibody:

AD7C-NTP

Immunogen:

Synthetic peptide of human AD7C-NTP

Full name:

Neuronal thread protein AD7c-NTP

Synonyms£º

AD7CNTP

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human tonsil

IHC Recommend dilution:

25-100

WB Predicted band size:

41 kDa

WB Positive control:

Human fetal brain tissue

WB Recommended dilution:

200-1000



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