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ÖÐÎÄÃû³Æ£ºÍÿ¹RRAGA¶à¿Ë¡¿¹Ìå  

Ó¢ÎÄÃû³Æ£º Anti-RRAGA rabbit ployclonal antibody

±ð      Ãû£º FIP1; RAGA; FIP-1

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´¢      ´æ£º Àä¶³£¨-20¡æ£©

ËÞ      Ö÷£º Rabbit

¿¹      Ô­£º RRAGA

·´Ó¦ÖÖÊô£º Human, Mouse, Rat

±ê¼ÇÎ Unconjugate

¿Ë¡ÀàÐÍ£º rabbit polyclonal

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Background:

Ras-related GTP-binding protein A is a protein that in humans is encoded by the RRAGAgene. Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death.

Applications:

ELISA, WB, IHC

Name of antibody:

RRAGA

Immunogen:

Fusion protein of human RRAGA

Full name:

Ras-related GTP binding A

Synonyms£º

FIP1; RAGA; FIP-1

SwissProt:

Q7L523

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human breast cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

37 kDa

WB Positive control:

Hepg2 and hela cells

WB Recommended dilution:

500-2000




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