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中文名称：小鼠抗HDAC4(N-term)单克隆抗体
技术规格
Background:
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.
Applications:
WB, IP
Name of antibody:
HDAC4(N-term)
Immunogen:
Fusion protein of human HDAC4
Full name:
histone deacetylase 4
Synonyms:
HD4; AHO3; BDMR; HDACA; HA6116; HDAC-4; HDAC-A
SwissProt:
P56524
WB Predicted band size:
119 kDa
WB Positive control:
Jurkat, K562 and Hela cell lysates
WB Recommended dilution:
1000-5000
