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中文名称：小鼠抗MYC单克隆抗体
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Background: |
c-Myc is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. |
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Applications: |
WB, IHC, IF |
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Name of antibody: |
MYC |
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Immunogen: |
Fusion protein of human MYC |
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Full name: |
v-myc avian myelocytomatosis viral oncogene homolog (MYC) |
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Synonyms: |
bHLHe39; c-Myc; MRTL; MYCC |
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SwissProt: |
P01106 |
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IHC positive control: |
human breast tissue and human liver tissue; carcinoma of human pancreas tissue and human thyroid tissue |
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IHC Recommend dilution: |
10-50 |
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WB Predicted band size: |
49 kDa |
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WB Positive control: |
Hela cell lysate |
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WB Recommended dilution: |
1000-5000 |
