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中文名称：小鼠抗HARS1单克隆抗体
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Background: |
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The gene is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter. The gene product is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012] |
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Applications: |
WB |
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Name of antibody: |
HARS1 |
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Immunogen: |
Fusion protein of human HARS1 |
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Full name: |
histidyl-tRNA synthetase 1 |
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Synonyms: |
HRS; HARS; CMT2W; USH3B |
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SwissProt: |
P12081 |
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WB Predicted band size: |
57 kDa |
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WB Positive control: |
T47D, COS7 and Hela cell lysates |
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WB Recommended dilution: |
1000-5000 |
