购物车
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021-54845833/15800441009
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Background: |
This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
ECH1 |
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Immunogen: |
Fusion protein of human ECH1 |
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Full name: |
enoyl-CoA hydratase 1 |
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Synonyms: |
HPXEL |
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SwissProt: |
Q13011 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human tonsil |
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IHC Recommend dilution: |
50-300 |
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WB Predicted band size: |
36 kDa |
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WB Positive control: |
Human fetal liver tissue, Hela, 293T, HepG2 and A549 cell lysates |
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WB Recommended dilution: |
500-2000 |
