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中文名称：小鼠抗FZD7单克隆抗体
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Background: |
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. |
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Applications: |
ELISA, WB |
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Name of antibody: |
FZD7 |
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Immunogen: |
Fusion protein of human FZD7 |
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Full name: |
frizzled class receptor 7 |
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Synonyms: |
FzE3 |
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SwissProt: |
O75084 |
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WB Predicted band size: |
64 kDa |
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WB Positive control: |
HepG2 whole cell lysate |
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WB Recommended dilution: |
500-2000 |
