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    ÖÐÎÄÃû³Æ : СÊó¿¹FCMRµ¥¿Ë¡¿¹Ìå

    Ó¢ÎÄÃû³Æ : Anti-FCMR mouse monoclonal antibody

    ±ð      Ãû : TOSO; FAIM3

    ¿¹      Ô­ : FCMR

    ´¢       ´æ : Àä¶³£¨-20¡æ£© ±Ü¹â

    ËÞ       Ö÷ : Mouse

    ·´Ó¦ ÖÖÊô : Human

    Ïà¹Ø Àà±ð : Ò»¿¹

    ±ê  ¼Ç  Îï : Unconjugate

    ¿Ë¡ ÀàÐÍ : mouse monoclonal


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    Background:

    May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.

    Applications:

    IHC

    Name of antibody:

    FCMR

    Immunogen:

    Fusion protein of human FCMR

    Full name:

    Fc fragment of IgM receptor (FCMR), transcript variant 1

    Synonyms:

    TOSO; FAIM3

    SwissProt:

    O60667

    IHC positive control:

    carcinoma of human thyroid tissue

    IHC Recommend dilution:

    30-150


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