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Background: |
This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. |
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Applications: |
WB |
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Name of antibody: |
EPOR(Phospho-Tyr368) |
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Immunogen: |
Peptide sequence around phosphorylation site of Tyrosine 368 (D-T-Y(p)-L-V) derived from Human Epo-R. |
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Full name: |
erythropoietin receptor |
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Synonyms： |
erythropoietin receptor |
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SwissProt: |
P19235 |
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WB Predicted band size: |
55 kDa |
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WB Positive control: |
K562 cells lysates |
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WB Recommended dilution: |
500-1000 |
